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Non conventional syntheses of heterocyclic compounds. 2 . Synthesis of 1 H ‐4,5‐dihydro‐1,3,4‐benzotriazepine derivatives
Author(s) -
Fusco Raffaello,
Marchesini Alessandro,
Sannicolò Franco
Publication year - 1986
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570230639
Subject(s) - chemistry , imine , aryl , stereochemistry , medicinal chemistry , organic chemistry , catalysis , alkyl
Abstract Arylazoanils carrying aromatic methyl or ethyl groups in the position ortho to the imine function thermally cyclize to give 1 H ‐4,5‐dihydro‐1,3,4‐benzotriazepine derivatives in fairly good yields. A study of the effect of the substituents on both the aryl rings is reported. The reaction is interpreted as an internal oxo‐reduction process.