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New functionalized N ‐heterocyclic carbene ligands for arylation of benzaldehydes
Author(s) -
Doğan Öznur,
Gürbüz Nevin,
Özdemir İsmail,
Çetinkaya Bekir
Publication year - 2009
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.48
Subject(s) - chemistry , carbene , catalysis , aryl , palladium , medicinal chemistry , combinatorial chemistry , organic chemistry , alkyl
AbstractNovel functionalized 1,3‐dialkylimidazolinium salts (LHCl) as NHC precursors have been prepared and successfully applied in palladium‐catalyzed arylation of benzaldehydes. The ortho position of aromatic aldehydes was directly and selectively arylated with aryl chlorides in the presence of a catalytic system prepared in situ from Pd(OAc) 2 , 1,3‐dialkylimidazolinium chlorides ( 2a , 2b , 2c ), and Cs 2 CO 3 . J. Heterocyclic Chem., (2009)