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An Improved Rapid and Mild Deoxygenation of Amine N ‐oxides
Author(s) -
Rajesh Y. B. R. D.
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3069
Subject(s) - deoxygenation , chemistry , amine gas treating , halogen , organic chemistry , reaction conditions , catalysis , alkyl
An improved mild and selective method for the deoxygenation of a variety of amine N ‐oxides has been carried out in the presence of silica gel under mild conditions at room temperature to afford corresponding amines in relatively good yields without purification. The reaction is tolerant of a variety of functional groups such as hydroxyl, ester, acid, carbonyl, and cyano groups, as well as halogens. This method would be of great utility to synthesize various pyridines and amines easily.