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Cre Recombinase Strains Used for the Study of Adipose Tissues and Adipocyte Progenitors
Author(s) -
Liu Jiaqi,
Xu Ziye,
Wu Weiche,
Wang Yizhen,
Shan Tizhong
Publication year - 2017
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.25675
Subject(s) - adipocyte , adipose tissue , biology , cre recombinase , progenitor cell , progenitor , genetics , microbiology and biotechnology , endocrinology , stem cell , gene , transgene , genetically modified mouse
Adipose tissues play important roles in whole body energy homeostasis and lifer span. Understanding the mechanisms of controlling adipose tissues development is significant for providing useful information to treat the worldwide epidemic of obesity and its associated metabolic diseases. Several different Cre transgenes have been generated and used for determining the origin of adipose tissues and the function of individual gene in regulating adipose growth and development. Here, we mainly review and discuss the efficiency and specific of those Cre recombinase mouse strains used for the study of adipose tissues and adipocyte progenitors. J. Cell. Physiol. 232: 2698–2703, 2017. © 2016 Wiley Periodicals, Inc.
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