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The Effect of Lithium Ion on the Regioselectivity of Substitution Reactions of Zinc Sulfolenylate
Author(s) -
Chou TaShue,
Chang ChinJyh
Publication year - 1998
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199800079
Subject(s) - chemistry , regioselectivity , lithium (medication) , zinc , electrophile , substitution reaction , electrophilic substitution , salt (chemistry) , ion , inorganic chemistry , medicinal chemistry , organic chemistry , catalysis , medicine , endocrinology
Abstract The addition of lithium cation to zinc sulfolenylates significantly changes the regioselectivity of its reaction toward carbonyl electrophiles. The more lithium salt is added, the more the reactions prefer to take place at the α‐position of the sulfolenylate.