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Alpha‐Fetoprotein Concentration in Maternal Serum and Abortion via VA and PGF 2 α
Author(s) -
Sande H. A.,
Fagerhol M.
Publication year - 1978
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/j.1879-3479.1977.tb00723.x
Subject(s) - medicine , abortion , vacuum aspiration , obstetrics , gestation , pregnancy , prostaglandin , gynecology , research methodology , endocrinology , family planning , population , genetics , environmental health , biology
ABSTRACT Most women undergoing abortion by vacuum aspiration (VA), extraamniotic prostaglandin instillation or vaginal prostaglandin suppositories showed a significant rise in their serum alpha‐fetoprotein (AFP) concentrations during the procedure. We suggest this rise is due to a fetomaternal hemorrhage during the abortion procedure. Few women undergoing VA before 9 weeks' gestation showed this rise in serum AFP. To avoid fetomaternal hemorrhage during pregnancy termination, we recommend abortion by VA in early pregnancy.