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Development of Pulmonary Edema Related to Heparin Administration
Author(s) -
AHMED S. SULTAN,
NUSSBAUM MURRAY
Publication year - 1981
Publication title -
the journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.92
H-Index - 116
eISSN - 1552-4604
pISSN - 0091-2700
DOI - 10.1002/j.1552-4604.1981.tb01762.x
Subject(s) - medicine , heparin , pulmonary edema , pulmonary embolism , myelofibrosis , edema , anesthesia , platelet , cardiology , bone marrow , lung
Bleeding, thrombocytopenia, and osteopenia are recognized as the side effects of heparin administration. We recently noted occurrence of pulmonary edema in a patient with myelofibrosis with myeloid metaplasia being treated with heparin for pulmonary embolism. The hypertensive episodes preceding left ventricular failure were considered related to serotonin released from the immunologically mediated lowering of platelets.