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Viloxazine and the Depressed Schizophrenic—Methodological Issues
Author(s) -
KURLAND ALBERT A.,
NAGARAJU ARRAMRAJU
Publication year - 1981
Publication title -
the journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.92
H-Index - 116
eISSN - 1552-4604
pISSN - 0091-2700
DOI - 10.1002/j.1552-4604.1981.tb01730.x
Subject(s) - medicine , schizophrenia (object oriented programming) , psychiatry , psychology
A pilot study of a small group of schizophrenic patients manifesting symptoms of a depressive nature was treated in a double‐blind study in which viloxazine or a placebo was administered in combination with either chlorpromazine or haloperidol. There appeared to be no difference between the viloxazine‐treated group and the placebo‐treated group, although the study raised some question as to the adequacies of the dosage utilized since there was an absence of any apparent side effects. In view of these issues concerning the clinical merit of the combination, this obviously requires further investigation.