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Rare involvement of submandibular gland by oral squamous cell carcinoma
Author(s) -
Chen TsengCheng,
Lo WuChia,
Ko JenqYuh,
Lou PeiJen,
Yang TsungLin,
Wang ChengPing
Publication year - 2009
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21039
Subject(s) - submandibular gland , medicine , neck dissection , pathology , stage (stratigraphy) , basal cell , cancer , lymph node , metastasis , dissection (medical) , carcinoma , primary tumor , radiology , biology , paleontology
Abstract Background The true involvement of the submandibular gland in primary oral cancer seems quite uncommon. Methods We retrospectively reviewed the pathologic records of 342 patients with oral squamous cell carcinoma who underwent wide excision of primary oral cancer and simultaneous neck dissection from January 2000 to December 2003. Results Of the 383 submandibular glands, only 7 (1.8%) exhibited tumor involvement. Of them, 5 glands were involved by direct extension from the primary tumor. One gland showed local invasion from an adjacent involved lymph node in level I and 1 was from intraglandular lymph node metastasis. All of these 6 tumors with submandibular gland involvement were T4 disease ( p = .0003) and the neck nodal status on each was more than N2b ( p < .0001). Conclusion The patients with early‐stage oral squamous cell carcinoma with preoperative N0 neck may be candidates for preservation of the submandibular gland. © 2009 Wiley Periodicals, Inc. Head Neck, 2009