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Sib‐pair analysis of the collaborative study on the genetics of alcoholism data set
Author(s) -
Jorgenson Eric,
Hinds David,
Risch Neil
Publication year - 1999
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.1370170732
Subject(s) - nonparametric statistics , genetics , statistical genetics , set (abstract data type) , allele , data set , biology , computational biology , computer science , statistics , mathematics , genomics , gene , genome , programming language
Abstract Nonparametric sib‐pair analysis was performed on the Collaborative Study on the Genetics of Alcoholism data set. Concordant and discordant pair groups were examined using the ASPEX package of programs. Allele sharing and multipoint lod scores for six comparison groups were obtained. Sharing and lod score patterns were not consistent with a simple genetic interpretation.