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Chemoselective Ru II ‐Catalyzed Synthesis of Aryl Thiocyanates and Step‐wise Double [2+2+2] Cycloadditions to 2‐Aryl Thiopyridines
Author(s) -
Bhatt Divya,
Kalaramna Pratibha,
Kumar Krishn,
Goswami Avijit
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202000691
Subject(s) - chemistry , aryl , cycloaddition , intermolecular force , catalysis , one step , medicinal chemistry , combinatorial chemistry , stereochemistry , organic chemistry , molecule , alkyl , art , visual arts
Ru II ‐catalyzed intermolecular double [2+2+2] cycloadditions of 1,6‐diynes and alkynylthiocyanates have been developed for the synthesis of 2‐aryl thiopyridines. Aryl thiocyanates were isolated chemoselectively as a result of initial intermolecular [2+2+2] cycloaddition product. The method offers operational simplicity and is atom economical in nature.