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Chromophoric Azo Reagents for Amino Acid and Peptide Labelling
Author(s) -
Fraga Susana M. B.,
Gonçalves Maria S. T.,
Moura João C. V. P.,
Rani Kavitha
Publication year - 2004
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200300692
Subject(s) - chemistry , labelling , lysine , peptide , serine , reagent , bioconjugation , amino acid , side chain , carboxylic acid , amino acid residue , stereochemistry , combinatorial chemistry , biochemistry , organic chemistry , peptide sequence , enzyme , polymer , gene
Abstract Four carboxylic azo dyes, with spectroscopic absorption peaks ranging from 400 to 500 nm, are presented as new markers for amino acid and peptide labelling at their N‐terminus. Labelling can also be performed at side‐chain residues as is exemplified with lysine and serine. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)