A Tetrakisquinoline Analog of Calcium Indicator Quin2 for Fluorescence Detection of Cd 2+ | Zendy

Mikata Yuji | Zendy; Kaneda Minori | Zendy; Tanaka Marin | Zendy; Iwatsuki Satoshi | Zendy; Konno Hideo | Zendy; Matsumoto Arimasa | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

A Tetrakisquinoline Analog of Calcium Indicator Quin2 for Fluorescence Detection of Cd 2+

Author(s) -

Mikata Yuji,

Kaneda Minori,

Tanaka Marin,

Iwatsuki Satoshi,

Konno Hideo,

Matsumoto Arimasa

Publication year - 2020

Publication title -

european journal of inorganic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.667

H-Index - 136

eISSN - 1099-0682

pISSN - 1434-1948

DOI - 10.1002/ejic.201901323

Subject(s) - chemistry , fluorescence , quinoline , benzene , methanol , ring (chemistry) , selectivity , calcium , nuclear chemistry , medicinal chemistry , stereochemistry , organic chemistry , physics , quantum mechanics , catalysis

Quin2 (2‐{2‐[bis(carboxymethyl)amino‐5‐methylphenoxy]methyl}‐6‐methoxy‐8‐[bis(carboxymethyl)amino]quinoline) is a well‐known fluorescent Ca 2+ indicator. In this study, we replaced its four carboxy groups with quinolines and deleted a methyl group on the benzene ring to afford TQquin2 [ N , N , N' , N' ‐tetrakis(2‐quinolylmethyl)‐8‐amino‐2‐(2‐aminophenoxy)methyl‐6‐methoxyquinoline]. In methanol solution, TQquin2 exhibited fluorescence enhancement toward Cd 2+ with excellent selectivity.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research