Premium
Cover Picture: Enamine Catalysis in Flow with an Immobilized Peptidic Catalyst (ChemSusChem 2/2013)
Author(s) -
Arakawa Yukihiro,
Wennemers Helma
Publication year - 2013
Publication title -
chemsuschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.412
H-Index - 157
eISSN - 1864-564X
pISSN - 1864-5631
DOI - 10.1002/cssc.201390006
Subject(s) - enamine , catalysis , chemistry , flow chemistry , front cover , stereoselectivity , cover (algebra) , combinatorial chemistry , organic chemistry , catalytic efficiency , organocatalysis , enantioselective synthesis , engineering , mechanical engineering
The front cover shows a flow system that operates with a highly effective immobilized peptidic catalyst, reported by Helma Wennemers and co‐workers from the ETH Zürich, Switzerland on page 242 . More than 600 turnovers and high stereoselectivities are achieved on a scale of >450 mmol (>100 g), without a significant drop of the activity or stereoselectivity of the immobilized peptidic catalyst. This high efficiency and sustainability of a flow system is unprecedented in the very active field of enamine catalysis and opens the way for more practical applications.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom