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Palladium‐Catalyzed Aza‐Wittig‐Type Condensation of Isoxazol‐5(4 H )‐ones with Aldehydes
Author(s) -
Okamoto Kazuhiro,
Shimbayashi Takuya,
Tamura Eisuke,
Ohe Kouichi
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201304211
Subject(s) - palladium , intramolecular force , catalysis , condensation , wittig reaction , chemistry , organic chemistry , condensation reaction , medicinal chemistry , physics , thermodynamics
This paper describes the development of a palladium‐catalyzed decarboxylative inter‐ and intramolecular condensation reaction of isoxazol‐5(4 H )‐ones with carbonyl compounds in the presence of PPh 3 , giving various 2‐azabuta‐1,3‐dienes or pyrroles in moderate to high yields.
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