Open AccessComplete remission of chemo‐refractory multiple‐metastatic upper tract urothelial carcinoma by autologous formalin‐fixed tumor vaccine
Author(s) -
Miyoshi Tatsu,
Kashiwabara Takeshi,
Asahi Atsuko,
Kataoka Tatsuji,
Maruyama Takashi,
Okada Rika,
Uemae Yoji,
Ohno Tadao
Publication year - 2017
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1179
Subject(s) - medicine , refractory (planetary science) , metastatic urothelial carcinoma , lymph node , lung , urothelial carcinoma , oncology , urology , cancer , bladder cancer , physics , astrobiology
Key Clinical Message A patient with chemo‐refractory multiple‐metastatic upper tract urothelial carcinoma ( UTUC ) treated by monotherapy with autologous formalin‐fixed tumor vaccine ( AFTV ) resulted in complete remission of the lung and para‐aortic lymph node metastases (ongoing >3 years after AFTV ). The tumor was immunohistologically negative for PD ‐L1. AFTV will be an attractive treatment option.