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Switching Modulation for Protein Labeling with Activatable Fluorescent Probes
Author(s) -
Sadhu Kalyan K.,
Mizukami Shin,
Hori Yuichiro,
Kikuchi Kazuya
Publication year - 2011
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201100137
Subject(s) - fluorescence , fluorescent protein , chemistry , fluorescent labelling , in vivo , biophysics , live cell imaging , molecular imaging , target protein , nanotechnology , computational biology , cell , green fluorescent protein , biochemistry , biology , materials science , gene , physics , microbiology and biotechnology , quantum mechanics
Fluorogenic protein‐labeling techniques have been successfully used in live‐cell imaging. Fluorescence derived from specific labeling can monitor the localization of proteins. Newly developed chemical techniques have addressed such specific incorporation of probes in the physiological environment. We conclude that some recent promising switching techniques should provide further molecular functional exploitation in vivo.