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One‐pot stepwise reductive amination reaction by N ‐coordinate sulfonamido‐functionalized Ru(II) complexes in water
Author(s) -
Kayacı Nilgün,
Dayan Serkan,
Özdemir Namık,
Dayan Osman,
Kalaycıoğlu Özpozan Nilgün
Publication year - 2018
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.4558
Subject(s) - chemistry , reductive amination , amination , aqueous solution , imine , solvent , transfer hydrogenation , crystal structure , fourier transform infrared spectroscopy , single crystal , proton nmr , medicinal chemistry , ruthenium , nuclear magnetic resonance spectroscopy , organic chemistry , catalysis , inorganic chemistry , crystallography , chemical engineering , engineering
New complexes of formula [RuCl( p ‐cymene)(L)] ( 7 – 12 ) were prepared with [RuCl 2 ( p ‐cymene)] 2 and pre‐synthesized N ‐arenesulfonly‐ o ‐phenylenediamines ( 1 – 6 ) and characterized using 1 H NMR, 13 C NMR, Fourier transform infrared and UV–visible spectroscopic techniques, and single‐crystal X‐ray diffraction analysis was performed for one complex ( 8 ). Complexes 7 – 12 were investigated in the reduced imine synthesis reaction (in the presence of HCOONa/HCOOH). The best turnover frequency values were found to be 100 h − 1 for 1 and 99 h −1 for 6 in the transfer hydrogenative reductive amination reaction of 4‐methoxyaniline and 3,4,5‐trimethoxybenzaldehyde. The most important feature of this reaction is that it is an environmental friendly procedure because of being conducted in an aqueous environment. That no organic solvent is used allows one to say that this reaction represents green chemistry.