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Copper‐catalyzed C‐N coupling reaction of tosylhydrazones
Author(s) -
Wu Xufeng,
Li Lingyu,
Jiang Wenlong,
Zhou Lihong,
Zeng Qingle
Publication year - 2018
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.4483
Subject(s) - chemistry , diazo , electrophile , catalysis , substrate (aquarium) , salt (chemistry) , combinatorial chemistry , copper , ligand (biochemistry) , coupling reaction , reactive intermediate , scope (computer science) , coupling (piping) , organic chemistry , mechanical engineering , biochemistry , oceanography , receptor , computer science , engineering , programming language , geology
Tosylhydrazones are a kind of labile and highly reactive compounds, which are apt to be transformed into reactive diazo compounds and then into extremely reactive carbenes under the basic condition. In order to fulfil the valuable C‐N coupling reaction, diaryliodonium salts are evaluated and prove to be a class of efficient electrophiles. The reaction with ligand‐free copper salt as catalyst shows a wide range of substrate scope. A plausible mechanism is proposed.
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