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Photoinduced Radical Borylation of Alkyl Bromides Catalyzed by 4‐Phenylpyridine
Author(s) -
Zhang Li,
Wu ZhongQian,
Jiao Lei
Publication year - 2020
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201912564
Subject(s) - borylation , chemistry , alkyl , catalysis , photochemistry , radical , nucleophile , pyridine , radical nucleophilic aromatic substitution , substrate (aquarium) , nucleophilic substitution , organic chemistry , aryl , nucleophilic aromatic substitution , oceanography , geology
Utilizing pyridine catalysis, we developed a visible‐light‐induced transition‐metal‐free radical borylation reaction of unactivated alkyl bromides that features a broad substrate scope and mild reaction conditions. Mechanistic studies revealed a novel nucleophilic substitution/photoinduced radical formation pathway, which could be utilized to trigger a variety of radical processes.

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