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Back Cover: Functional Mechanically Interlocked Molecules: Asymmetric Organocatalysis with a Catenated Bifunctional Brønsted Acid (Angew. Chem. Int. Ed. 38/2017)
Author(s) -
Mitra Raja,
Zhu Hui,
Grimme Stefan,
Niemeyer Jochen
Publication year - 2017
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201707711
Subject(s) - bifunctional , catenane , chemistry , stereoselectivity , organocatalysis , catalysis , molecule , stereochemistry , combinatorial chemistry , organic chemistry , enantioselective synthesis
A catenane‐based organocatalyst shows excellent stereoselectivity in the transfer hydrogenation of quinolines. In their Communication on page 11456 ff., J. Niemeyer and co‐workers report the first application of a catenane catalyst in asymmetric catalysis. The bifunctional catenane shows superior stereoselectivity in comparison to its non‐interlocked analogues. DFT calculations indicate the involvement of both catalytically active groups as the reason for the high stereoselectivity.