z-logo
Premium
Total Synthesis of Paecilospirone
Author(s) -
Yuen TszYing,
Yang SungHyun,
Brimble Margaret A.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201103117
Subject(s) - neutrality , construct (python library) , aldol reaction , key (lock) , computer science , content (measure theory) , information retrieval , chemistry , combinatorial chemistry , world wide web , organic chemistry , mathematics , political science , law , computer security , programming language , catalysis , mathematical analysis
Neutrality is the best policy : Key features of the first total synthesis of paecilospirone include an anti ‐selective, lactate‐derived aldol reaction, and a double deallylation/spirocyclization conducted at neutral pH to construct the sensitive hydroxy‐substituted benzannulated spiroacetal (see scheme; Bn=benzyl, TBS= tert ‐butyldimethylsilyl, TES=triethylsilyl).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here