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Multiple Catalysis with Two Chiral Units: An Additional Dimension for Asymmetric Synthesis
Author(s) -
Piovesana Susy,
Scarpino Schietroma Daniele M.,
Bella Marco
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201005955
Subject(s) - dimension (graph theory) , catalysis , enantioselective synthesis , transformation (genetics) , computer science , combinatorial chemistry , nanotechnology , biochemical engineering , chemistry , materials science , mathematics , organic chemistry , engineering , pure mathematics , biochemistry , gene
Abstract This Minireview focuses on asymmetric reactions mediated by two distinct chiral catalysts (chiral multiple catalysis). Initially, this approach appears unconventional, but indeed it allows a fast multidimensional optimization and fine‐tuning of the catalytic system required to perform a given transformation. Herein, this emerging concept is presented and its potential applications are highlighted.