Premium
Dementia in Latin America: Paving the way toward a regional action plan
Author(s) -
Parra Mario Alfredo,
Baez Sandra,
Sedeño Lucas,
Gonzalez Campo Cecilia,
SantamaríaGarcía Hernando,
Aprahamian Ivan,
Bertolucci Paulo HF,
Bustin Julian,
Camargos Bicalho Maria Aparecida,
CanoGutierrez Carlos,
Caramelli Paulo,
Chaves Marcia L. F.,
Cogram Patricia,
Beber Bárbara Costa,
Court Felipe A.,
Souza Leonardo Cruz,
Custodio Nilton,
Damian Andres,
de la Cruz Myriam,
Diehl Rodriguez Roberta,
Brucki Sonia Maria Dozzi,
Fajersztajn Lais,
Farías Gonzalo A.,
De Felice Fernanda G.,
Ferrari Raffaele,
de Oliveira Fabricio Ferreira,
Ferreira Sergio T.,
Ferretti Ceres,
Figueredo Balthazar Marcio Luiz,
Ferreira Frota Norberto Anizio,
Fuentes Patricio,
García Adolfo M.,
Garcia Patricia J.,
de Gobbi Porto Fábio Henrique,
Duque Peñailillo Lissette,
Engler Henry Willy,
Maier Irene,
Mata Ignacio F.,
GonzalezBillault Christian,
Lopez Oscar L.,
Morelli Laura,
Nitrini Ricardo,
Quiroz Yakeel T.,
Guerrero Barragan Alejandra,
Huepe David,
Pio Fabricio Joao,
Suemoto Claudia Kimie,
Kochhann Renata,
Kochen Silvia,
Kumfor Fiona,
Lanata Serggio,
Miller Bruce,
Mansur Leticia Lessa,
Hosogi Mirna Lie,
Lillo Patricia,
Llibre Guerra Jorge,
Lira David,
Lopera Francisco,
Comas Adelina,
AvilaFunes José Alberto,
Sosa Ana Luisa,
Ramos Claudia,
Resende Elisa de Paula França,
Snyder Heather M.,
Tarnanas Ioannis,
Yokoyama Jenifer,
Llibre Juan,
Cardona Juan Felipe,
Possin Kate,
Kosik Kenneth S.,
Montesinos Rosa,
Moguilner Sebastian,
Solis Patricia Cristina Lourdes,
FerrettiRebustini Renata Eloah de Lucena,
Ramirez Jeronimo Martin,
Matallana Diana,
MbakileMahlanza Lingani,
Marques Ton Alyne Mendonça,
Tavares Ronnielly Melo,
Miotto Eliane C,
MunizTerrera Graciela,
MuñozNevárez Luis Arnoldo,
Orozco David,
Okada de Oliveira Maira,
Piguet Olivier,
Pintado Caipa Maritza,
Piña Escudero Stefanie Danielle,
Schilling Lucas Porcello,
Rodrigues Palmeira André Luiz,
Yassuda Mônica Sanches,
SantacruzEscudero Jose Manuel,
Serafim Rodrigo Bernardo,
Smid Jerusa,
Slachevsky Andrea,
Serrano Cecilia,
SotoAñari Marcio,
Takada Leonel Tadao,
Grinberg Lea Tenenholz,
Teixeira Antonio Lucio,
Barbosa Maira Tonidandel,
Trépel Dominic,
Ibanez Agustin
Publication year - 2021
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1002/alz.12202
Subject(s) - latin americans , dementia , psychological intervention , transformative learning , political science , socioeconomic status , action plan , action (physics) , economic growth , psychology , medicine , population , environmental health , nursing , biology , ecology , developmental psychology , disease , pathology , law , physics , quantum mechanics , economics
Abstract Across Latin American and Caribbean countries (LACs), the fight against dementia faces pressing challenges, such as heterogeneity, diversity, political instability, and socioeconomic disparities. These can be addressed more effectively in a collaborative setting that fosters open exchange of knowledge. In this work, the Latin American and Caribbean Consortium on Dementia (LAC‐CD) proposes an agenda for integration to deliver a Knowledge to Action Framework (KtAF). First, we summarize evidence‐based strategies (epidemiology, genetics, biomarkers, clinical trials, nonpharmacological interventions, networking, and translational research) and align them to current global strategies to translate regional knowledge into transformative actions. Then we characterize key sources of complexity (genetic isolates, admixture in populations, environmental factors, and barriers to effective interventions), map them to the above challenges, and provide the basic mosaics of knowledge toward a KtAF. Finally, we describe strategies supporting the knowledge creation stage that underpins the translational impact of KtAF.