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Sleep‐disordered breathing in Beckwith–Wiedemann syndrome: Three patients
Author(s) -
Kansagra Sujay,
D'Cruz O'Neill,
Noah Terry L.,
Vaughn Bradley V.
Publication year - 2012
Publication title -
american journal of medical genetics part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.064
H-Index - 112
eISSN - 1552-4833
pISSN - 1552-4825
DOI - 10.1002/ajmg.a.35628
Subject(s) - polysomnography , medicine , obstructive sleep apnea , hypoventilation , breathing , hypoxemia , sleep disordered breathing , beckwith–wiedemann syndrome , sleep (system call) , apnea , sleep apnea , sleep and breathing , craniofacial , pediatrics , anesthesia , respiratory system , psychiatry , biochemistry , gene expression , chemistry , computer science , dna methylation , gene , operating system
Abstract Beckwith–Wiedemann syndrome is associated with craniofacial abnormalities that may predispose patients to sleep‐related breathing disorders. There is limited literature on the polysomnography findings for children with this syndrome. Three patients with Beckwith–Wiedemann syndrome underwent polysomnography in our sleep lab and were found to have a variety of sleep‐disordered breathing that ranged from obstructive apnea to isolated REM sleep‐related hypoxemia–hypoventilation without obstructive apnea. Suspicion for sleep‐disordered breathing should be high in children with Beckwith–Wiedemann syndrome. © 2012 Wiley Periodicals, Inc.