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Hydroamination on homogeneous and heterogeneous catalysts: Kinetic study
Author(s) -
Müller Thomas E.,
Lercher Johannes A.,
Van Nhu Nguyen
Publication year - 2003
Publication title -
aiche journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.958
H-Index - 167
eISSN - 1547-5905
pISSN - 0001-1541
DOI - 10.1002/aic.690490119
Subject(s) - hydroamination , isomerization , catalysis , chemistry , piperidine , amine gas treating , homogeneous , kinetic energy , homogeneous catalysis , organic chemistry , thermodynamics , physics , quantum mechanics
This kinetic analysis compares homogeneous and heterogeneous catalysts for the cyclization of 6‐aminohex‐1‐yne. The reaction was studied as a model for the direct addition of amine NH bonds to CC multiple bonds (hydroamination). Kinetic modeling showed that the metal‐catalyzed hydroamination reaction is followed by a proton‐catalyzed isomerization of the primary reaction product, 2‐methylene‐piperidine, to the thermodynamically more stable 2‐methyl‐1,2‐dehydropiperidine.
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