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Discovery of Herbacetin as a Novel SGK1 Inhibitor to Alleviate Myocardial Hypertrophy (Adv. Sci. 2/2022)
Author(s) -
Zhang Shujing,
Wang Yingchao,
Yu Min,
Shang Ye,
Chang Yanxu,
Zhao Hong,
Kang Yu,
Zhao Lu,
Xu Lei,
Zhao Xiaoping,
Difrancesco Dario,
Baruscotti Mirko,
Wang Yi
Publication year - 2022
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202270009
Subject(s) - sgk1 , medicine , muscle hypertrophy , cardiology , glucocorticoid
Herbacetin In article number 2101485, Xiaoping Zhao, Yi Wang, and co‐workers describe that herbacetin (HBT) derived from traditional Chinese medicine Rhodiola rosea (known as “golden root” in Europe) is identified as a novel SGK1 inhibitor to significantly alleviate myocardial hypertrophy, which brings dawn to patients with heart failure as well as other SGK1‐driven diseases.

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