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Chemically Tunable Lensing of Stimuli‐Responsive Hydrogel Microdomes
Author(s) -
Ehrick J. D.,
Stokes S.,
BachasDaunert S.,
Moschou E. A.,
Deo S. K.,
Bachas L. G.,
Daunert S.
Publication year - 2007
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200601969
Subject(s) - phenothiazine , self healing hydrogels , materials science , covalent bond , acrylamide , swelling , ligand (biochemistry) , biophysics , combinatorial chemistry , polymer chemistry , polymer , chemistry , monomer , organic chemistry , biochemistry , receptor , medicine , composite material , pharmacology , biology
Chemically tunable hydrogel microlenses have been developed from acrylamide hydrogels based on covalently bound hinge‐motion binding proteins, like calmodulin, and low affinity ligands, i.e. phenothiazine. Initially the protein binds to phenothiazine forming chemical crosslinks within the hydrogel, which are released in the presence of the higher affinity ligand chlorpromazine resulting in the swelling of the microlenses.
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