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Coiled‐Coil Peptide‐Based Assembly of Gold Nanoparticles
Author(s) -
Stevens M. M.,
Flynn N. T.,
Wang C.,
Tirrell D. A.,
Langer R.
Publication year - 2004
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.200306430
Subject(s) - coiled coil , materials science , nanoparticle , nanotechnology , peptide , nanostructure , electromagnetic coil , flexibility (engineering) , colloidal gold , biophysics , nuclear magnetic resonance , electrical engineering , statistics , physics , mathematics , biology , engineering
The coiled‐coil‐based assembly of gold nanoparticles (see Figure and cover) is demonstrated. Control over the assembly and disassembly of nanostructures is achieved under mild conditions (near‐neutral pH and ambient temperature). The flexibility in design afforded by varying the peptide sequence to produce coiled coils with different stabilities is also highlighted by the generation of more stable binary nanoparticle systems with controlled spacing and architecture.