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Bioengineered Gastrointestinal Tissue: Bioengineered Gastrointestinal Tissues with Fibroblast‐Induced Shapes (Adv. Funct. Mater. 6/2021)
Author(s) -
Zhou Linna,
RuizPuig Carlos,
Jacobs BrittanyAmber,
Han Xiaoyue,
Lisle Richard,
Bayley Hagan,
Lu Xin
Publication year - 2021
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.202170036
Subject(s) - materials science , regenerative medicine , fibroblast , tissue engineering , seeding , microbiology and biotechnology , lipid bilayer , nanotechnology , biomedical engineering , bilayer , biophysics , cell culture , biology , membrane , stem cell , medicine , biochemistry , genetics , agronomy
Bioengineered gastrointestinal tracts have potential applications both in regenerative medicine and disease modelling. In article number 2007514, Hagan Bayley, Xin Lu, and co‐workers produce collagen tubes with designed shapes by using a lipid bilayer supported droplet networks. Complex shapes are generated by controlling the seeding density of fibroblasts. Furthermore, when seeded with fibroblasts and epithelial cells, the tubular structures form sub‐epithelial and epithelial layers that line their lumens.