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Author(s) -
Hannink Jurry M.,
Cornelissen Jeroen J. L. M.,
Farrera Joan A.,
Foubert Philippe,
De Schryver Frans C.,
Sommerdijk Nico A. J. M.,
Nolte Roeland J. M.
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20011217)40:24<4519::aid-anie4519>3.0.co;2-#
Subject(s) - cover (algebra) , engineering , mechanical engineering
Abstract The cover picture shows the process of building functional amphiphilic protein–polymer hybrids in a modular fashion. Monolayers of biotinylated polystyrene (purple) bind the protein streptavidin (blue), resulting in the formation of giant amphiphiles. The remaining free binding sites are subsequently used to associate biotinylated biomacromolecules (yellow), such as the iron‐storage protein ferritin. The use of covalent conjugates of streptavidin and horseradish peroxidase leads to the formation of reactive surfaces, which are capable of catalyzing organic reactions. Further details on these giant amphiphiles are reported by Nolte and co‐workers on p. 4732 ff.