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Investigation of Sugar‐Binding Sites in Ternary Ligand−Copper(II)−Carbohydrate Complexes
Author(s) -
Striegler Susanne,
Tewes Elfi
Publication year - 2002
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/1099-0682(20022)2002:2<487::aid-ejic487>3.0.co;2-d
Subject(s) - chemistry , diethylenetriamine , copper , ethylenediamine , ligand (biochemistry) , polymer chemistry , ternary operation , inorganic chemistry , aqueous solution , carbohydrate , metal , monomer , polymer , organic chemistry , combinatorial chemistry , biochemistry , receptor , computer science , programming language
Abstract Evaluation of the binding interactions between a template (such as a carbohydrate) and a functional monomer (such as a metal complex) is one of the key steps during the design of molecularly imprinted polymers. Since we are interested in the development of carbohydrate‐imprinted polymers as functional enzyme mimics, we have evaluated the binding interactions of several carbohydrates with [(diethylenetriamine)copper(II)] dinitrate ( 1 ), [ N ‐{(2‐hydroxyethyl)ethylenediamine}copper(II)] dichloride ( 8 ), and [{4‐( N ‐vinylbenzyl)diethylenetriamine}copper(II)] diformate ( 13 ) in aqueous solution. The binding sites of epimeric carbohydrates in complex formation with different copper(II) complexes have been investigated for the first time. The ternary ligand−copper(II)−carbohydrate complexes produced have been characterized by determination of their stoichiometry and their binding strength, by UV/Vis spectroscopy at alkaline pH.