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Conservative approaches to the management of localized prostatic cancer
Author(s) -
Whitmore Willet F.
Publication year - 1993
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19930201)71:3+<970::aid-cncr2820711412>3.0.co;2-6
Subject(s) - medicine , life expectancy , stage (stratigraphy) , cancer , conservative management , prostate cancer , gynecology , management of prostate cancer , endocrine system , intensive care medicine , surgery , hormone , paleontology , population , environmental health , biology
Background . The management of early stage prostatic cancer is controversial. Methods . Pertinent literature concerning the conservative management of early stage prostatic cancer by early endocrine therapy (EET) or by deferred treatment (DT) was reviewed. Results . EET has not been systematically studied. Available evidence suggests that early stage prostatic cancer often progresses slowly and that DT results in a cancer‐specific mortality of approximately 80% at 10 years. Conclusions . EET warrants clinical investigation. DT is a management option, at least in patients with a life expectancy of 10 years or less.
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