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Hepatitis B related childhood hepatocellular carcinoma. Childhood hepatic malignancies
Author(s) -
De Potter Christian R.,
Robberecht Eddy,
Laureys Genevieve,
Cuvelier Claude A.
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19870801)60:3<414::aid-cncr2820600322>3.0.co;2-s
Subject(s) - hbcag , hepatoblastoma , medicine , hbsag , hepatocellular carcinoma , hepatitis b virus , hepatitis b , hepatitis , liver cancer , antigen , virology , immunology , virus
Abstract The case of hepatocellular carcinoma (HCC) with foci of hepatoblastoma in a 7‐year‐old boy, the son of a hepatitis B surface antigen (HBsAg) carrier mother, is described. Twelve other malignant liver tumors in children were also reviewed for HBsAg and hepatitis B core antigen (HBcAg). Both were negative in all (nine) hepatoblastomas. One of three HCC demonstrated positivity for HBsAg. These cases illustrate the importance of hepatitis B virus infection in early childhood and stress the need for careful screening in pregnant women, irrespective of ethnic backgrounds.