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Occlusion and infection in broviac catheters during intensive cancer therapy
Author(s) -
Lazarus Md Hillard M.,
Lowder James N.,
Herzig Roger H.
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19831215)52:12<2342::aid-cncr2820521230>3.0.co;2-z
Subject(s) - medicine , cancer , occlusion , intensive care medicine , surgery
Abstract Before administration of intensive cytotoxic therapy, 90 central venous catheters were inserted into 80 patients with malignancies. Twenty‐seven episodes of bacteremia and fungemia occurred during 96 treatment courses. The majority of these infections were due to gram‐positive bacteria (45%) or fungi (22%), although gram‐negative organisms accounted for 33%. Catheter occlusion occurred in patients receiving intravenous phenytoin, but blood products could be infused without difficulty. An increase in gram‐positive bacteremias in patients with these catheters and drug‐induced catheter occlusion must now be appreciated. Cancer 52:2342‐2348, 1983.