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Gonadotropin‐secreting renal carcinoma
Author(s) -
Golde David W.,
Schambelan Morris,
Weintraub Bruce D.,
Rosen Saul W.
Publication year - 1974
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197404)33:4<1048::aid-cncr2820330423>3.0.co;2-a
Subject(s) - medicine , luteinizing hormone , endocrinology , human chorionic gonadotropin , gonadotropin , radioimmunoassay , kidney , placental alkaline phosphatase , hormone , alkaline phosphatase , biology , biochemistry , enzyme
Abstract Tumors of the kidney are known to cause an impressive array of extrarenal manifestations. A patient with a primary malignant renal tumor associated with the production of chorionic gonadotropin (hCG), placental lactogen, and placental alkaline phosphatase is described. The gonadotropic hormone was identified as hCG by a recently developed radioimmunoassay that distinguishes hCG from pituitary luteinizing hormone. This report establishes another humoral syndrome to be considered in association with renal tumors.