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The possible role of riboflavin deficiency in epithelial neoplasia. II. Effect on skin tumor development
Author(s) -
Wynder Ernest L.,
Chan Po C.
Publication year - 1970
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197012)26:6<1221::aid-cncr2820260607>3.0.co;2-i
Subject(s) - riboflavin , carcinogenesis , medicine , tumor promotion , cancer research , physiology , endocrinology , cancer , biochemistry , biology
Temporary riboflavin deficiency in young mice tends to enhance chemically‐induced skin carcinogenesis. When mice are kept on a normal diet, the injection of riboflavin before initiation or promotion does not affect the tumor induction by the two‐step mechanism of chemical carcinogenesis.
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