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Synthesis of poly(amino acid)‐urethane copolymers. Effects of solvents and initiators
Author(s) -
Uchida Shinji,
Oohori Tomeyoshi,
Tanaka Tamotsu,
Suzuki Masahiro,
Shirai Hirofusa
Publication year - 1999
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/(sici)1521-3935(19991201)200:12<2645::aid-macp2645>3.0.co;2-3
Subject(s) - triethylamine , polymer chemistry , copolymer , chemistry , dimethylformamide , polymerization , amine gas treating , solvent , polymer , organic chemistry
Abstract The synthesis of the copolymer of poly(amino acid)‐urethane(PAU) by replacing the solvent 1,2‐dichloroethane with N , N ‐dimethylformamide causes gelation, namely, the solution of the PAU intermediate is fluid, but gelation is caused when triethylamine, the polymerization initiator of γ ‐methyl‐ L ‐glutamate‐ N ‐carboxylic anhydride(NCA), is added to the solution, resulting in PAU which does not exert fluidity. In case of polymerizing only NCA in dimethylformamide using triethylamine as the initiator, the product PMLG is also gelatinous. When using a primary amine or diamine as initiator, a fluid turbid solution of PMLG was obtained. Infrared(IR) spectra and X‐ray diffraction of the PMLG suggested that the PAU gelation is due to the partial association of the α ‐helix chain of the PMLG at both ends of the copolymer.