Open AccessSensitivity and Specificity of Fluorescent Immunoguided Neoplasm Detection in Head and Neck Cancer Xenografts
Author(s) -
Brian D. Kulbersh
Publication year - 2007
Publication title -
archives of otolaryngology - head and neck surgery
Language(s) - English
Resource type - Journals
eISSN - 1538-361X
pISSN - 0886-4470
DOI - 10.1001/archotol.133.5.511
Subject(s) - medicine , cetuximab , pathology , head and neck cancer , antibody , cancer , minimal residual disease , neoplasm , biopsy , fluorescence , monoclonal antibody , immunology , bone marrow , physics , quantum mechanics
To determine whether fluorescently labeled anti-epidermal growth factor (EGFR) antibody could be used to detect residual disease and to guide surgical resections by comparing the sensitivity and specificity of optical fluorescence imaging with the sensitivity and specificity of histopathologic evaluation.
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