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Motivation: Due to the central role of protein structure in molecularrecognition, great computational efforts are devoted to modeling proteinstructures and motions that mediate structural rearrangements. The size,dimensionality, and non-linearity of the protein structure space presentoutstanding challenges. Such challenges also arise in robot motion planning,and robotics-inspired treatments of protein structure and motion areincreasingly showing high exploration capability. Encouraged by such findings,we debut here ROMEO, which stands for Robotics prOtein Motion ExplOrationframework. ROMEO is an open-source, object-oriented platform that allowsresearchers access to and reproducibility of published robotics-inspiredalgorithms for modeling protein structures and motions, as well as facilitatesnovel algorithmic design via its plug-and-play architecture.  Availability and implementation: ROMEO is written in C++ and is available inGitLab (https://github.com/). This software is freely available under theCreative Commons license (Attribution and Non-Commercial).  Contact: amarda@gmu.edu

ROMEO: A Plug-and-play Software Platform of Robotics-inspired Algorithms for Modeling Biomolecular Structures and Motions