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The most commonly isolated bacteria from endodontically infected teeth are anaerobic, especially black-pigmented gram negative organisms. However, facultative microorganisms such as Enterococcus faecalis, aerobes like Staphylococcus aureus, and yeasts like Candida albicans are considered by many to be the most resistant species, and possible causes of root canal treatment failure. Irrigating solutions and intracanal medicaments are required to eradicate microorganisms, and over a period of time, a variety of chemicals have been introduced. The alarming incidence of antibiotic resistance amongst the microbes, has led to the search of alternative antimicrobial drugs from medicinal plants to treat these infections. Curcuma longa (turmeric) belonging to the Zingiberaeceae family, has been used for thousands of years as a flavouring agent, a medicinal herb, and a dyeing agent. Owing to its antimicrobial properties, it can prove to be useful in endodontics as well. Therefore; in the present study, aqueous and hydro-alcoholic extracts of the roots of Curcuma longa rhizome were prepared and solutions of different concentrations of the extracts were made. Antimicrobial susceptibility tests were performed using the agar well diffusion method. The Minimum inhibitory concentration (MIC) and the Minimum bactericidal concentration (MBC) were calculated. 2.3% sodium hypochlorite solution was used as the positive control. Both extracts showed good antimicrobial properties against the endodontic pathogens. Hence, its future use as an endodontic irrigant or medicament should be considered and further evaluated.

Evaluation of Antimicrobial Activity of Aqueous and Hydro-Alcoholic Curcuma Longa Extracts against Endodontic Pathogens