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The present study was conducted to find out the correlation of dietary deficiency of vitamin B6, vitamin B12 and folic acid on development of coronary artery disease (CAD). This study was carried out on 172 male patients of age group between 45-65 years having both genetic and non-genetic background for CAD from Kolkata, India. Present study showed that BMI, SBP, DBP, LDL-c, triglyceride, total cholesterol, fasting and post prandial blood glucose level, homocysteine, CPK and CPK-MB enzyme levels were higher while HDL-c, LVEF and hemoglobin levels were lower than recommended normal values in both subject groups. Daily consumption of carbohydrate, vitamin B12, vitamin B6 and folic acid levels of both subject groups were found to be lower while consumption of fat was higher than recommended values. Present study showed that there was a significant correlation between intake of vitamin B6, vitamin B12 and folic acid and risk factors for CAD in both groups. All these findings indicate that folic acid, vitamin B6 and vitamin B12 deficiency may have influence in developing risk for CAD.

Effect of dietary deficiency of vitamin B6, vitamin B12 and folic acid on the development of coronary artery disease in adult Indian male patients