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A study had been conducted for antibacterial and cytotoxic activities against secondary metabolite of Artemisia saline resulted from the association between sponge Aaptos suberiptoides and bacteria. The experimental study was conducted by isolating sponge Aaptos suberitoides-associated bacteria, which were then extracted using n-hexane, ethylacetate and methanol as solvents. The bacteria were isolated with pour plate method and the resulting secondary metabolites were brought under antibacterial assay for their activities against the bacteria Staphylococcus aureus, Escherichia coli, Candida albicans and Aspergillusniger and cytotoxic activities against A. saline. Conclusion. All extracts showed weak antibacterial activities with inhibiting diameter ranging from 6.32 ±0.27 - 9.95 ± 0.09. An assay for A saline showed that ethyl-acetate extracts were more toxic than methanolic extracts and n-hexane, with an LC50 value of 21,93µg/mL, 65.02 µg/mL, and 178.22µg/mL, respectively.

Evaluation of Antibacterial Activities of Secondary Metabolites Produced by Aaptos suberiptoides associated bacteria