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Moringaoleifera is a pan-tropical species that is reputed to possess a number of nutritional and medicinal properties. On the other hand, honey is widely known for its anti-trypanocidal effects. The effect of various doses of aqueous extract of Moringaoleifera seed on the activities of the White Blood Cells (WBC) and Red Blood Cells (RBC) was investigated. Daily-dose administration of the Moringa seed treated water (1 - 10 mg/ml) to different rat groups for 21 days resulted in significant increase (P > 0.05) in the activities of the RBC and WBC were seen to have their influence in fighting the disease Trypanosomiasis. Histopathological studies revealed the presence of marked aggregation of bile canaliculi around the portal vein of the liver. Aqueous extract of Moringaoleifera leaves also delayed the proliferation of the parasites. Honey has properties of boosting the immune system, its anti-inflammatory action, antioxidant activity and stimulation of cell growth. Anaemia and serum biochemical changes are common features of African trypanosomosis. We investigated whether honey has protective effect on some liver functions and blood parameters affected by trypanosome infection. The serum albumin concentration in infected untreated rats increased significantly (p<0.05) compared with control whereas treatment with honey returned this effect to normal values. Keyword:Moringaoleifera seed extract, honey, toxicity, parasitaemia, metabolic enzymes.

Benchmark study on effect of Trypanosome brucei using Moringaoleifera seed extract and Honey as treatment measure(s)