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The present study was carried out to find out the antibacterial activity and phytochemical study of Mangifera indica (leaf) and Musa paradisiaca (root) extracts against some common pathogens. In this study, the leaf and root extracts of M. indica and M. paradisiaca respectively were subjected to screening against Staphylococcus aureus, Escherichia coli, Streptococcus pneumoniae, Proteus mirabilis and Pseudomonas aeruginosa. Antimicrobial analysis was done by using agar well diffusion and the MIC values were determined by using macro-broth dilution method. The ethanol extract of M.paradisiaca produced the highest antibacterial activity against S.aureus (10.40 + 0.04) followed by the ethanol extract of M.indica against P.mirabilis (9.52 + 0.06). The antimicrobial activity of standard antibiotics Gentamycin and Trimethoprim were studied in comparison with the plant extracts. The phytochemical analysis showed the presence of alkaloid, flavonoid, tannins, saponins, glycosides and anthraquiones. Biological active compounds present in these plant extracts have always been of great interest to scientist as they play an important physiological and etiological role hence they are of great commercial interest with multiple application on pharmaceutical industries.

iosr journal of pharmacy and biological sciences

Assessment of the phytochemical components of Mangifera indica (leaf) and Musa paradisiaca (roots) extracts and their antibacterial activity against some common pathogenic bacteria.