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Protein sequences have been considered for a long time as highly complex sequences from the informational content point of view. We study about the randomness of protein and difficulty of protein compression. In this report, we propose a lossless compression method to reduce the random or repeated sequence of protein. Our proposed method is the enhancement of Dictionary Based Algorithm proposed by D. Adjeroh and F. Nan. They have shown better result in compressing protein. Our repeat reduction method shows improved results in compressing three types of protein sequences from MJ (Methanococcus jannaschii), HI (Haemophilus influenzae) and HS (Homo sapiens). The experimental results demonstrate that the performance of the proposed method is superior compared to Dictionary based algorithm.

A New Approach of Protein Sequence Compression using Repeat Reduction and ASCII Replacement