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The synthesis of a series of 7-acylamido cephalosporins having a substituted furyl moiety in the side chain is described. These new cephalosporins were examined in vitro for antibacterial activity and evaluated for resistance to inactivation by beta-lactamases.

Semisynthetic .BETA.-lactam antibiotics III. Cephalosporin derivatives in the furyl series. Chemical and microbiological properties.