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Introducción: La 3,4-Methylenedioxypyrovalerone (mdpv) es un componente de lasdenominadas sales de baño, aparecidas en el mercado a final de la década del 2000debido a la falta de precursores de síntesis de mdma, y su uso va en aumento. El ob-jetivo de este trabajo es clarificar sus características farmacológicas y potencialidadesadictivas. Método: Mediante búsquedas en PubMed, 21 estudios relacionados con laquímica, farmacología o potencial adictivo del mdpv fueron seleccionados. Resulta-dos: El mdpv muestra ser capaz de inducir una potente hiperlocomoción, preferenciascondicionadas, sensibilización conductual, autoadministración y altos puntos de corteen pruebas de razón progresiva. Conclusión: Los estudios revisados apuntan a queel mdpv es un potente psicoestimulante con un potencial adictivo similar al de la cocaí-na o la metanfetamina. Su abuso continuado podría llevar a una epidemia de adictosal mdpv.Introduction: 3,4-Methylenedioxypyrovalerone (mdpv) is a major component of the newpsychoactive substances termed “bath salts”. These substances appeared on the drugmarket at the end of the last century given the lack of mdma precursors, caused by itsworldwide prosecution by governments and police agencies, and its growing use. Thegoal of this work was to clarify its pharmacological features and addiction-like potentiali-ties. Methods: By PubMed searches, 21 studies related to mdpv chemistry, pharmacology or addictive features were selected. Results: mdpv is seen to be able to inducepotent hyperlocomotion, conditioned place preference, behavioural sensitisation, self-administration and high breakpoints in progressive ratio schedules. Conclusion: Thereviewed studies indicate that mdpv is a powerful psychostimulant with a similar addictivepotential to that of cocaine or methamphetamine. Its abuse can lead to an epidemic ofmdpv addicts

Locomotor activating effects and addiction-like features of MDPV as assessed in preclinical studies: a review.