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Only 20-30% of patients with cisplatin refractory or relapsed germ cell cancer will remain continuously disease free with salvage chemotherapy. Paclitaxel is a potent anticancer agent against a variety of solid cancers. The present study investigated the chemotherapy with paclitaxel in combination with nedaplatin, which is a derivative of cisplatin, and ifosphamide as salvage chemotherapy for cisplatin refractory germ cell cancer.

SALVAGE CHEMOTHERAPY WITH PACLITAXEL, IFOSPHAMIDE AND NEDAPLATIN FOR RELAPSED OR REFRACTORY GERM CELL CANCER