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The appearance of M. lepraemurium as seen by electronmicro­ scopy has been described by McFadzean and Valentine (1958-9). Two forms of the bacilli were observed, one the normal form (Fig. 1 ) and the other a degenerate non-viable form (Fig . 2). It was shown that an estimate of the percentage of degenerate forms present gave an indication as to the viability of a suspension. This paper describes the results of the application of similar techniques to M. leprae. A preliminary communication has been given of the results (McFadzean and Valentine, 1 958).

THE EXAMINATION AND THE DETERMINATION OF THE VIABILITY OFMYCOBACTERIUM LEPRAEBY ELECTRONMICROSCOPY